Jubilant Pharmova (Previously Jubilant Life Sciences)

Notes from Q1 concall

  • 200 cr revenue in Qtr is linked to covid, possibly 100 cr more in coming Qtrs.
  • per Mgmt both YoY as well as QoQ there is performance improvement in core biz
  • RoCE and RoE around 16% , expect FY22 end to see it much higher
  • Demerger is more of internal restructuring ( for now denied plan of spin-off in near future) to create better operations efficiency- however the restructuring gives them a high yield and high growth asset construct as well
  • Demand environment is good ( except Liver tests in us) - as covid related one offs go down, other biz areas which are slow will pickup thus growth continues
  • Alert for roorkee facility - clear root cause not explained even though warning was already there - explanation given was on lines of areas outside warning letter were also called out for lack of cleanliness- which mgmt didn’t think will happen.
  • Mitigation of revenue impact - max 1-2 month impact on areas which were cleared from alert scope( to secure third party validation…) - this is majority revenue out of facility so didn’t seem concerned per them
  • Interesting call out was that Roorkee facility capacity which gets unused till alert resolution - same will be used in RoW markets
  • Radio pharma biz has been in red but strategy is to use this as distribution channel to cross sell new products as well as continue to turn around by ways of operations optimization.
  • Good demand on CDMO continues- company is keen to build and grow it.
  • Novel drug biz to continue losing money - last qtr concall mgmt called out monetization in 1.5+yr, same stance continues
  • Balance sheet healthier

1600 cr Qtry revenue even after taking out covid one offs should continue doing 1300-1400 cr qtrly run rate, operating leverage by higher utilization should support margin profile. Difficult to see any reasons why Annual EPS will be lesser than 30- 35 range and EBDITA at 20% conservatively( ideally As CDMO share grows this will take it up as segment margins around 40%) , after normalizing Qtrly profit runrate comes to 150 -180 cr( PAT 600-700 cr for FY22), Market cap is at 11000 cr, implying PE of 17-18 type.

Risk reward seems favorable, there is something about both Jub twins where larger market is still not giving due valuations, probably few more Qtrs to build that conviction. Ingrevia has lesser complexity and variable at play hence seems better positioned.

Invested - tracking position, looking weak on charts as of now, 660 of recent lows need to be watched for bounce back

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Please go through their most recent annual report and investor presentation and also through the latest reports posted by some fund houses, you will get most of your questions answered.

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Simvastatin manufactured by Jubilant Generics is in high demand . Stock is very attractive in terms of valuation.

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30 September 2021

Jubilant Therapeutics Announces Successful Completion of Pre-IND Meeting with FDA for its Novel Dual LSD1 and HDAC6 Inhibitor JB1-802

JubilantTxPressReleasePre-ind.pdf (202.7 KB)

DISCL. INVESTED.

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Q2 call

What all is wrong- There seems to be all sort of headwinds possible, have happened/ happening for them.

  • Pharma Sector is out of favor and have headwinds,
  • Perceived RM cost impact from China and margins contraction
  • Import alert on Roorkee plant, full remediation to take few qtrs, exempted products also not being produced yet
  • Generics price erosion and some sartan products recall due to impurity
  • EBDITA QoQ reduction
  • Too complex of business ( too many moving parts or segments)
  • Coming out of a demerger ( chemical biz) and headed to some more restructuring ( CDMO unit)
  • Covid impacted biz of US( radiopharma) yet to fully recover and continued cases of US covid cases still impacting
  • Contarct manufacturing of Covid products reduction ( helped in capacity utilization and margins front in last 2 Q)
  • Novel drug considered a drag as long upfront investments and binary outcomes

Valuation - less than 1.5X sales, 15 PE and 7X EBDITA on annualized basis, 20%+ EBDITA even at subdued performance.

What is improving and can improve in near term

  • Let’s look at consolidated biz view

Full details here

Some broader pointer, Q2 call inferences and what is changing, what is being ignored by market, future growth triggers etc

  • Good Management pedigree- part of Bhartiya group ( Jubilant ingrevia, Jubilant food works being some of other listed companies - both have created decent wealth for investors)

  • KSM and solvent issue was acknowledged (44:00 in concall) but didn’t seem a structural issue, also relatively manageable one with pass on to customer

  • Import alert - exempted products ramp up started from first week of Oct after recertification completion - net of which it is low single digit impact on that plan revenue ( $35M is gross asset block), they are also working with third party manufacturers to supply banned products, also plant supplies can be used in RoW, on alert resolution plant to submit early CY 22 post which FDA visit to re inspect - net net negligible financial impact

  • Generics underperformance ( 20% revenue) - per mgmt price pressure in US has cyclical pattern and currently at bottom of cycle, can see 1-2 Qtr subdued performance though API has picked up sequential, Q2 was higher base last year and that will normalize as well going ahead

  • CRDS is dark horse with massive growth YOY of 44% on revenue and 73% EBDITA, high margins of 33% , H1 numbers also impressive , New CEO joined them, Noida expanded capacity came online and further Capex on same announced - as this biz becomes sizable, narrative will evolve

  • Net debt down from 1700 cr+ in Mar 21 to approx 1000 cr in Sept 21(100 odd cr incrementalin working capital but to normalize in next Qtrs), interest cost and rate( below 5%) both down

  • Tax rates were high in H1 at 34% , to come down at 25% over next 3 years - profit figure to look better boosting EPS

  • We have seen value creation out of Jubilant Ingrevia demerger - it’s too early but new CRDS post restructuring will build a high growth and margin asset base.

  • Novel drug can be seen as drag but can also be a high risk high reward optionality- Last concall Mr Bhartiya did indicate ability to monetize if needed, and working on investments to come in for funding ( reminds of Suven life type situation)

  • Specialty pharma will have CDMO carved out thus CRDS and CDMO will start to look good growth and margins biz - together a sizable chunk

  • speciity pharma - Radiopharma and Allegry seem to be on recovery and are based in US geo, multiple Capex coming online here as well in next 2 yrs( radiopharmacy biz breakeven expected by end of this year). This adds to complexity in terms of not being typical India pharma/API game - per numbers does deliver 20%+ margins and double digit growth in mixed bag performance, to improve per mgmt on margins trajectory and Capex already done coming online.

  • 700 cr+ Capex in near future Guidance.

Tracking position

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Covaxin approal by WHO might be a big trigger as Jubilant will produce Covaxin for US and Canada, CRDS margins will surprise upwards in coming years. Holding for long long term in PF 7% allocation

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@Cshar thats quite an allocation conviction and patience in current market situations, would be good to hear your thoughts on future possibilities and performance for everyone’s benefit.

Also would you have some materials or pointers to better understand their US/Canada biz ( radiopharma, allegry etc) that you can share with this group.

On your point of WHO covaxin approval benefits - did you mean US and Canada sponsered LMIC countries related procurements? As most of citizens of developed countries are already vaccinated and even for booster shots they may incline towards Moderna or Pfizers, rather than an India originated vaccine.

Thanks.

What is the relation of WHO approval to US and Canada market?

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[Bharat Biotech has entered into a definitive agreement with OcugenInc, a US-based biopharmaceutical company, to co-develop, supply, and commercialise, its Covaxin for the American and Canadian markets. Ocugen has selected Jubilant as partner in USA.

Vaccine Jabs will continue till next year, being much cheaper than Pfizer and moderna, this might be a potential revenue opportunity.

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As for covid vaccines people may not look at the cheaper one but efficient one. If covaxin efficacy and longevity is more than the mRNA vaccines then only it would stand a chance against them.

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WHO approval will not have any weight, it has to be approved by the FDA for US use. FDA has already denied emergency use authorization to it. We should have some definitive answers, what trial they are running, when they will get approval, can go into production, what type of involvement Jubilant has in this all process?

Also US price will have added cost associated to it. It can not be 4-5$ range or even 10-12$.

Accumulation by RJ

Available at 1.5X sales and 7X EBDITA at Q2 annualized. Clearly Mr Market has a solid disliking !!

Tracking position

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Jubilant pharmova is actually not trading at P/E of 11. This calculation is inclusive of Dec’20 and March’21 quarter which includes Jublilant Ingrevia. One has to be clear on that aspect.

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Does this mean that they have gotten approval for the drug or they have got approval for the trial of the drug (Sorry am not very well versed with the pharma industry and this USFDA thing and the article is also not helping me understand :pensive:)

As per the article- clearance received to move to next stage of clinical trials…seems a step forward in the right direction, among may more to come ( hopefully)

Not an expert on the topic and request views of seniors/experts

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This is approval for commencing trails, nothing that translates in financial in immediate future.

The Phase 1/2a trial is an open-label, two-part dose escalation and expansion study designed to define the safety profile and preliminary activity of JBI-802 in participants with advanced solid tumors. The study population will include patients with locally advanced or metastatic solid tumors whose disease has failed prior standard therapy. Expansion cohorts of participants with SCLC, NEPC, and other neuroendocrine-derived cancers will be enrolled.

However it is an imp milestone

  • Management is walking the talk
  • Biotech prowess is demonstrated - new molecules are very high risk disproportionately high rewards game( suven life is at it for ages and had to eventually demerge given years of patience it takes)- very few take this path and in general investment community may see this a drag ( though some pure play biotech innovators do get sizable funding and valuations in developed countries)
  • Establshes credentials to get some external funding ( key monitorable)

One can understand better in terms of opportunity size and mgmt plans here for Therapeutics division

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Notes from AR- 2021-22 iro Jubilant Pharmova -

  1. Revenues from Pharma business at 5789 cr vs 5714 cr. CRO revenues at 305 cr vs 251 cr. EBITDA at 1414 cr vs 1585 cr. EBITDA margins at 23 pc vs 27 pc YoY. Depreciation and amortisation at 349 cr vs 339 cr. Finance cost stood at 184 vs 199 cr YoY. PAT at 573 cr vs 677 cr YoY with an EPS of Rs 36.

  2. Pharma segment - Manufactures and supplies radio pharmaceuticals with a network of 48 radio pharmacies in US, Allergy immunotherapy, Contract manufacturing of sterile injectables and non sterile products, APIs and solid dose formulations through 6 manufacturing facilities that cater to North America, Europe and other geographies.

Sub segment ( within Pharma segment ) wise performance -

(a) Speciality Pharma - includes radio Pharma and immunotherapies - Sales at 2303 cr vs 3019 cr YoY…primarily due lower number of lung scans due COVID and competition.

(aa) Radio Pharma - Manufacture, supply and distribution of radiopharma products for diagnosis and treatment of various disease.Company specialises in Lung, cardiac, Bone and Thyroid imaging products as well as thyroid disease therapy. Has second largest radio pharmacy chain in US with total pharmacies at 48 distributing nuclear medicine products to national Group Purchasing Organisations ( GPOs). Serves 4 million patients per yr. Radio pharmacies complement radio Pharma manufacturing business and provides it direct access to hospital networks. Company further enhancing marketing and business development efforts for Ruby-Fill ( used for PET imaging ) installations as Covid situation improves. Also launched Ruby Fill in Europe.

Company has entered into a strategic alliance with SOFIE biosciences with 25 pc equity holding enabling SOFIE to grow its Theranostic ( combo of diagnosis and therapy using two radio Pharma materials. First one used to diagnose, second one used to treat ) pipeline and support novel PET diagnostic manufacturing and distribution within US. SOFIE is a leader in fast growing molecular Theranostic field. SOFIE has 14 radio pharmacies for PET scans. It also has CMO facility to make Theranostic molecules. SOFIE also owns 70 pc exclusive rights of a proprietary FAPI ( Fibroblast activation protein inhibitor ) used to treat and diagnose a variety of oncology disease. SOFIE and Jubilant together intend to be a Theranostic powerhouse.

In FY 20-21, Radio pharma division reported sales of 1915 cr vs 2607 cr last yr.

(ab) Allergy immunotherapy - Sells in US and exports to several intl mkts including Canada, Europe and Australia. It is a differentiated business of manufacturing and marketing Allergenic extracts. Sole producer and supplier of Venom immunotherapy in US. This business was also affected by COVID. Sales stood at 388 vs 411 cr YoY.

(b) CMO - 04 manufacturing locations in US. Offers CMO of sterile injectables, ampoules, sterile ointments, creams and liquids. Business witnessed good growth during the year with sales at 1394 cr vs 895 cr …helped by CMO of Covid vaccines. New area of growth identified by the company - sterile ophthalmic products.Setting up a new line for the same in Canada. Investing aprox 650 cr in Washington to expand sterile manufacturing capabilities.

(c) APIs - Makes APIs in CVS, CNS, Anti Infectives and Anti Depressants categories. Sales stood at 615 vs 640 cr. Several cost and process efficiency programs are being undertaken for various APIs as a part of life cycle management.

(d) Generics - Only present in solid dose formulations. Mostly focussed on regulated markets led by US. Business drives benefits from in house APIs. Makes formulations at Roorkee and Salisbury in US. Roorkee facility received import alert in Jul 21. USFDA has exempted Olanzapine, Resperidone, Meclizine, Valsartan and Spironolactone from import alert thus affecting only 3 pc of total company revenues. Total revenues from this segment was 1476 cr vs 1159 cr. Company sees significant growth opportunities in RoW mkts. Europe continues to remain a strong mkt for the company.

  1. CRO business - Provides contract research and development business under Jubilant Biosys ltd. Sales stood at 305 cr vs 251 cr YoY.

  2. Proprietary Novel Drugs - working in Onco and immunology fields. 04 of company assets / molecules are in advanced pre clinical stages and would transition to clinic early next yr. Company intends to create shareholder value in this business via private/public equity raise/ partnerships in the next 18-24 months.

Disc : holding from higher levels

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Share value going down and down. Anything that I missed?

I think it has more to do with Pharma as a sector going out of favor then anything else …when companies like Divi’s can correct from 5500 to 4000 without any reason or bad news , correction in rest of the lot too happens.

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